Maternal depressive symptoms related to Epstein-Barr virus reactivation in late pregnancy

作者：Zhu, Peng; Chen, Yu Jiang; Hao, Jia Hu; Ge, Jin Fang; Huang, Kun; Tao, Rui Xue; Jiang, Xiao Min; Tao, Fang Biao^*

来源：Scientific Reports, 2013, 3(1): 3096.

DOI：10.1038/srep03096

We examined the relationship between maternal depressive symptoms in late pregnancy and Epstein-Barr virus reactivation before delivery. In this prospective observational study, prevalence of Epstein-Barr virus reactivation within one week before delivery was compared between 163 pregnant women with depressive symptoms at 33 to 34 weeks of gestation and a computer-generated control group of 163 pregnant healthy women without depressive symptoms. Depressive symptoms at 33 to 34 weeks of gestation were significantly related to the prevalence of Epstein-Barr virus reactivation before delivery after adjustment for potential confounders (adjusted OR=2.74, 95%CI: 1.23-6.08). Compared to that in the control group, the prevalence of Epstein-Barr virus reactivation was higher in women with depressive symptoms accompanied by higher negative coping (24.2% compared with 7.9%; adjusted OR=3.67, 95%CI: 1.47-9.16). Maternal depressive symptoms in late pregnancy are associated with Epstein-Barr virus reactivation, and this association could be moderated by maternal coping style.

• 出版日期2013-10-31
• 单位安徽医科大学