A clean synthesis of 1,4-diarylquinoline derivatives catalyzed by TEBAC in aqueous media

作者:Wang Xiang Shan*; Zhang Mei Mei; Jiang Hong; Shi Da Qing; Tu Shu Jiang
来源:Journal of the Chinese Chemical Society, 2007, 54(4): 1033-1039.

摘要

A series of 1,4-diarylquino line derivatives were synthesized by the reaction of arylmethylidene-malononitriles or 2-cyano-3-aryl- I -acrylate and 3-arylamino-5,5-dimethylcyclohex-2-enone in aqueous media at 100 degrees C catalyzed by TEBAC. Meanwhile, the water medium was chosen as green solvent.