Soy Isoflavone Equol Perpetuates Dextran Sulfate Sodium-Induced Acute Colitis in Mice

作者:Sakai Tohru*; Furoku Sakina; Nakamoto Mariko; Shuto Emi; Hosaka Toshio; Nishioka Yasuhiko; Sone Saburo
来源:Bioscience Biotechnology and Biochemistry, 2011, 75(3): 593-595.
DOI:10.1271/bbb.100710

摘要

The effects of the soy isoflavones, genistein, daidzein and equol, on experimental colitis were examined. Equol severely perpetrated dextran sulfate sodium (DSS)-induced colitis as evaluated by the weight loss. Production of the anti-inflammatory cytokine, IL-10, from T cells was decreased in the equol-treated mice. The results show that the soy isoflavone, equol, played an important role in the inflammatory response in the gastrointestinal tract.

  • 出版日期2011-3