Approach to osteomyelitis treatment with antibiotic loaded PMMA

作者:Zhang Wentao; Lei, Guangyu; Liu, Yang*; Wang, Wei; Song, Tao; Fan, Jinzhu
来源:Microbial Pathogenesis, 2017, 102: 42-44.
DOI:10.1016/j.micpath.2016.11.016

摘要

Background: To reduce the incidence of osteomyelitis infection, local antibiotic impregnated delivery systems are commonly used as a promising and effective approach to deliver high antibiotic concentrations at the infection site. Objective: The objective of this review was to provide a literature review regarding approach to osteomyelitis treatment with antibiotic loaded PMMA. Study design: Literature study regarding osteomyelitis treatment with antibiotic loaded carriers using key terms Antibiotic, osteomyelitis, biodegradable PMMA through published articles. Hands searching of bibliographies of identified articles were also undertaken. Conclusion: We concluded that Antibiotic-impregnated PMMA beads are useful options for the treatment of osteomyelitis for prolonged drug therapy.