Health-related quality of life in adults reporting arthritis: analysis from the National Health Measurement Study

作者：Khanna Dinesh^*; Maranian Paul; Palta Mari; Kaplan Robert M; Hays Ron D; Cherepanov Dasha; Fryback Dennis G

来源：Quality of Life Research, 2011, 20(7): 1131-1140.

DOI：10.1007/s11136-011-9849-z

• Health-Related Quality of Life
• HRQOL
• Arthritis
• National Health Measurement Study
• Self-reported arthritis
• EQ-5D
• SF-6D
• HUI2
• HUI3
• HALex
• QWB
• QWB-SA

Background Arthritis is the leading cause of disability in the United States. We assess the generic health-related quality-of-life (HRQOL) among a nationally representative sample of US adults with and without self-reported arthritis.
Methods The NHMS, a cross-sectional survey of 3,844 adults (35-89 years) administered EuroQol-5D (EQ-5D), Health Utilities Index Mark 2 (HUI2) and 3 (HUI3), SF-36v2 (TM), Quality of Well-being Scale self-administered form (QWB-SA), and the Health and Activities Limitations index (HALex) to each respondent via a telephone interview. Weighted multiple linear regression was used to generate age-gender-arthritis-stratified unadjusted HRQOL means and means adjusted for sociodemographic, socioeconomic covariates and comorbidities by arthritis-age category.
Results The estimated population prevalence of self-reported arthritis was 31%. People with arthritis were more likely to be woman, older, of lower socioeconomic status, and had more self-reported comorbidities than were those not reporting arthritis. Adults with arthritis had lower HRQOL on six different indexes compared with adults without arthritis, with overall differences ranging from 0.03 (QWB-SA, age-group 65-74) to 0.17 (HUI3, age-group 35-44; all P-value < .05).
Conclusion Arthritis in adults is associated with poorer HRQOL. We provide age-related reference values for six generic HRQOL measures in people with arthritis.

• 出版日期2011-9