An iron-oxygen intermediate formed during the catalytic cycle of cysteine dioxygenase

作者：Tchesnokov E P; Faponle A S; Davies C G; Quesne M G; Turner R; Fellner M; Souness R J; Wilbanks S M; de Visser S P^*; Jameson G N L^*

来源：Chemical communications, 2016, 52(57): 8814-8817.

DOI：10.1039/c6cc03904a

Cysteine dioxygenase is a key enzyme in the breakdown of cysteine, but its mechanism remains controversial. A combination of spectroscopic and computational studies provides the first evidence of a short-lived intermediate in the catalytic cycle. The intermediate decays within 20 ms and has absorption maxima at 500 and 640 nm.

• 出版日期2016