Adherence to treatment, by active ingredient, in patients over 65 years on multiple medication

作者：Nunez Montenegro Antonio J; Montiel Luque Alonso; Martin Aurioles Esther; Torres Verdu Barbara; Lara Moreno Celinda; Gonzalez Correa Jose Antonio

来源：Atencion Primaria, 2014, 46(5): 238-245.

DOI：10.1016/j.aprim.2013.10.003

• Multiple medication
• Active ingredient
• Patient safety
• Elderly
• Adherence

Aim: To assess the level of adherence, by active ingredient, to treatment and associated factors in polymedicated patients over 65 years-old. %26lt;br%26gt;Design: Observational, descriptive and cross-sectional study over polymedicated patients over 65 years of the Costa del Sol Health District and the North Malaga Health Area. The study was performed between January 2011 and September 2012 on 375 subjects obtained by simple random sampling from lists provided by each health centre. Data was collected by means of an interview with structured questions. Informed consent was given and signed by all patients before interview. %26lt;br%26gt;Study variables: Main results variable adherence to treatment (Morisky-Green%26apos;s test). %26lt;br%26gt;Predictable variables: Prescription by active ingredient, socio-demographic variables, health care centre variables, and treatment associated variables. %26lt;br%26gt;A descriptive analysis of variables was performed. Statistical inference was determined using univariate analysis (t test of Student or Mann-Whitney U, and Chi-squared), and controlling for confounding factors by multivariate analysis (linear and logistic regression). %26lt;br%26gt;Results: The result for therapeutic compliance was 51.7%. No statistically significant differences were observed as regards sex and age. A relationship was found in those who resided in rural areas (P=.001), lived with family (P%26lt;.05), and were not at risk of suffering from anxiety (P=.046). %26lt;br%26gt;Conclusions: We found similar patient adherence to treatment despite the prescribing generic drugs. Failure to therapeutic compliance was greater in those patients who lived by themselves, in a city close to the coast, or in those patients who were at risk of suffering from anxiety.

• 出版日期2014-5