A simplified method of opacifying and mixing acrylic cement for percutaneous vertebroplasty: A clinical and in vitro study

作者：Teng GJ^*; He SC; Deng G; Guo JH; Fang W; Zhu GY

来源：CardioVascular and Interventional Radiology, 2005, 28(5): 570-577.

DOI：10.1007/s00270-004-0126-1

• vertebroplasty, percutaneous
• vertebral fracture, osteoporosis
• vertebrae, tumors
• bone cement, opacifier

The objective of this study was to simplify the opacifying mixing process of the bone cement and contrast used for percutaneous vertebroplasty (PVP). We performed a biomechanical study of polymethyl methacrylate (PMMA) (Corinplast (TM) 3) using three different mixtures of PMMA, monomer, and contrast: group I, 2: 1; group II, 3:2; group III, 3:2:1 ratio of powder/monomer/iodinated contrast (Omnipaque). In vitro biomechanical testing of ultimate compressive strength was carried out in all samples. Following the conclusion of a proper bone cement mixture regimen drawn from the in vitro study, PVP was performed in 125 patients: 58 with cancer, 12 with hemangioma, and 54 with osteoporotic fracture. The ultimate compressive strength in group III was decreased by 38% compared to groups II and I. Proper fluoroscopic visualization was achieved in all PVP procedures using this mixture. There were no major complications associated with injection of the cement mixture. Complete (CR) and partial response (PR) was obtained in 64% and 32.8%, respectively. No further vertebral collapse occurred during follow-up. The regimen using iodinated contrast for cement visualization during PVP provides a simple and convenient new method for mixing. Although the biomechanical strength is altered by the contrast medium added, it seems insignificant in clinical practice based on the authors' limited experience.

• 出版日期2005-10
• 单位东南大学