MRI for Staging Lymphoma: Whole-Body or Less?

作者：Kwee Thomas C^*; Akkerman Erik M; Fijnheer Rob; Kersten Marie Jose; Zsiros Jozsef; Ludwig Inge; Bierings Marc B; Vermoolen Malou A; van Leeuwen Maarten S; Stoker Jaap; Nievelstein Rutger A J

来源：Journal of Magnetic Resonance Imaging, 2011, 33(5): 1144-1150.

DOI：10.1002/jmri.22549

• MRI
• whole-body
• Hodgkin lymphoma
• non-Hodgkin lymphoma
• staging

Purpose: To assess whether whole-body MRI detects more clinically relevant lesions (i.e., leading to a change in Ann Arbor stage) than an MRI protocol that only Includes the head/neck and trunk (i.e., from cranial vertex to groin, excluding the arms) in patients with lymphoma.
Materials and Methods: One hundred consecutive patients with newly diagnosed lymphoma prospectively underwent T1-weighted and T2-weighted short inversion time inversion recovery whole-body MRI. The number of lymphomatous sites at MRI with a field of view (FOV) limited to the head/neck and trunk, and the additional number of lymphomatous sites at whole-body MRI and their Influence on Ann Arbor stage were determined.
Results: At MRI with a FOV limited to the head/neck and trunk, 507 sites were classified as lymphomatous. At whole-body MRI, 7 additional sites outside the head/neck and trunk in 7 patients (7.0%; 95% confidence interval: 3.4-13.8%) were classified as lymphomatous, but Ann Arbor stage never changed.
Conclusion: Whole-body MRI did not detect any clinically relevant lesions outside the FOV of an MRI protocol that only includes the head/neck and trunk. Therefore, it may be sufficient to only include the head/neck and trunk when using MRI for staging lymphoma.

• 出版日期2011-5