Nesting sub-studies and randomised controlled trials within birth cohort studies

作者：Golding Jean^*

来源：Paediatric and Perinatal Epidemiology, 2009, 23: 63-72.

DOI：10.1111/j.1365-3016.2008.00994.x

• birth cohort studies
• sub-samples
• randomised controlled trials
• validation
• environmental measures
• biological sampling
• nested case-control studies

Although birth cohort studies can stand on their own, there are a number of different types of sub-studies that can add value to the overall project. These can be summarised within four main categories: (A) more detailed observations of relatively small subgroups aimed at describing mechanisms and processes; (B) nested case-control studies; (C) use of detailed observations to validate data collection by questionnaire or interview; (D) randomised controlled trials. For each category we give examples of ways in which they have been employed in current pregnancy birth cohort studies.

• 出版日期2009-7