A case of rare multiple drug sensitization involving several mechanisms of hypersensitivity

作者：Pralong P^*; No**aum A; Rouzaire P; Ben Said B; Nicolas J F; Berard F

来源：Revue Francaise d'Allergologie, 2013, 53(7): 601-604.

DOI：10.1016/j.reval.2012.10.003

• Immediate and delayed allergic hypersensitivity to drugs
• Non-allergic hypersensitivity to drugs
• Synergystin
• Lincosanids

We describe the case of a patient with three types of drug hypersensitivity: immediate allergic hypersensitivity to pristinamycin, delayed allergic hypersensitivity to clindamycin, and non-allergic hypersensitivity to betalactams. Diagnoses were made on the very suggestive clinical history, and relevant skin and biological tests. This is the first reported case involving three mechanisms of hypersensitivity. The pathophysiological mechanisms remain unclear. In the patient, the diagnosis could be suspected from the history, which emphasizes the role of anamnesis in the choice of the kind of allergy testing.

• 出版日期2013-11