QbD‐oriented development and validation of a bioanalytical method for nevirapine with enhanced liquid–liquid extraction and chromatographic separation

作者：Sarwar Beg; Vandna Chaudhary; Gajanand Sharma; Babita Garg; Sagar Suman Panda; Bhupinder Singh

来源：Biomedical Chromatography, 2016, 30(6): 818-828.

DOI：10.1002/bmc.3613

• analytical quality by design
• risk estimation matrix
• extraction
• robustness
• stability

Abstract(#br)The present studies describe the systematic quality by design (QbD)‐oriented development and validation of a simple, rapid, sensitive and cost‐effective reversed‐phase HPLC bioanalytical method for nevirapine in rat plasma. Chromatographic separation was carried out on a C18 ...

• 出版日期2016