Antimicrobial activity of Argemone ochroleuca Sweet (Chicalote)

作者：Daniel Reyes Francisco; Jimena Pena Celia; C****es Margarita; Jimenez Manuel; Meraz Samuel; Hernandez Tzasna

来源：Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas, 2011, 10(2): 139-146.

• Antibacterial activity
• Antifungal activity
• Argemone ochroleuca
• Berberine
• Papaveraceae
• Tepotzotlan
• Mexico

Argemone ochroleuca Sweet (Papaveraceae) is used to treat eye infection, respiratory and dermatological disorders in Tepotzotlan, State of Mexico (Mexico). The aim of this work was to investigate antimicrobial activity of hexane, ethyl acetate and methanol extracts from aerial parts of A. ochroleuca. The antimicrobial activity was evaluated against thirteen bacteria and nine fungal strains. Only methanol extract showed antimicrobial activity. S. aureus (MIC= 125 mu g/mL) and C. neoformans (MIC= 500 mu g/mL) were the most sensitive strains. The bioassay-guide purification of the methanolic extract resulted in the isolation and identification of the isoquinoline alkaloid berberine. The present study confirms the antimicrobial activity of methanolic extract of A. ochroleuca.

• 出版日期2011-3