Attraction by repulsion: compounds with like charges undergo self-assembly in water that improves in high salt and persists in real biological fluids

作者：Garnett Graham A E; Daze Kevin D; Diaz Jorge A Pena; Fagen Noah; Shaurya Alok; Ma Manuel C F; Collins Mary S; Johnson Darren W; Zakharov Lev N; Hof Fraser^*

来源：Chemical communications, 2016, 52(13): 2768-2771.

DOI：10.1039/c5cc10527g

We report a family of highly anionic calixarenes that form discrete homo-dimeric assemblies in pure water, that get stronger in high salt solutions, and that remain assembled in complex, denaturing solutions like real urine. The results reveal the potential of like-charged subunits for self-assembly in high-salt solutions and biological fluids.

• 出版日期2016