A solid-state control system for dynein-based ciliary/flagellar motility

作者:King Stephen M*
来源:The Journal of Cell Biology, 2013, 201(2): 173-175.
DOI:10.1083/jcb.201302077

摘要

Ciliary and flagellar beating requires the coordinated action of multiple dyneins with different enzymatic and motor properties. In this issue, Yamamoto et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201211048) identify the MIA (modifier of inner arms) complex within the Chlamydomonas reinhardtii axoneme that physically links to a known regulatory structure and provides a signaling conduit from the radial spokes to an inner arm dynein essential for waveform determination.

  • 出版日期2013-4-15