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摘要
An efficient synthesis of 5-amino-7-aryl-3-oxo-8-(phenylsulfonyl)-thiazolo[3,2-a]pyridine-6-carbonitriles was conducted utilizing multicomponent condensation reaction of malononitrile, aromatic aldehydes and 2-phenylsulfonylmethylenethiazolidin-4-one in one pot. Depending on the equivalence of the aldehyde, two different products were obtained from moderate to excellent yields. Thirteen novel structures were characterized by physical and spectroscopic methods (m.p., Rf, IR, NMR and mass analysis).
- 出版日期2013-3
