A Case of Rectal Cancer Arising from Long-Standing Prolapsed Mucosa of the Rectum

作者：Nonaka Takashi; Inamori Masahiko^*; Kessoku Tadaomi; Ogawa Yuji; Yanagisawa Shogo; Shiba Tadahiko; Sakaguchi Takashi; Gotoh Eiji; Maeda Shin; Nakajima Atsushi; Atsukawa Kazuhiro; Takahasi Hisao; Akasaka Yoshikiyo

来源：Internal Medicine, 2011, 50(21): 2569-2573.

DOI：10.2169/internalmedicine.50.5924

• mucosal prolapse syndrome
• solitary rectal ulcer syndrome
• rectal cancer
• malignant transformation

Mucosal prolapse syndrome (MPS) has been recognized as a chronic benign inflammatory disorder, characterized mainly by rectal mucosal prolapse. Disorders representing this condition include solitary rectal ulcer syndrome (SRUS), rectal prolapse, proctitis cystica profunda, and inflammatory cap polyps. The gross appearance of rectal MPS can be occasionally misinterpreted as rectal cancer. In contrast, there have been a few reports of colorectal cancer originating from prolapsed mucosa. Herein, we report a case of MPS associated with two independent rectal cancers extending into the submucosal layer. We speculate that long-standing MPS may increase the risk of malignant transformation.

• 出版日期2011