Low effectiveness of seasonal influenza vaccine in preventing laboratory-confirmed influenza in primary care in the United Kingdom: 2014/15 mid-season results

作者：Pebody R G; Warburton F; Ellis J; Andrews N; Thompson C; von Wissmann B; Green H K; Cottrell S; Johnston J; de Lusignan S; Moore C; Gunson R; Robertson C; McMenamin J; Zambon M

来源：Eurosurveillance, 2015, 20(5): 6-12.

DOI：10.2807/1560-7917.es2015.20.5.21025

In 2014/15 the United Kingdom experienced circulation of influenza A(H3N2) with impact in the elderly. Mid-season vaccine effectiveness (VE) shows an adjusted VE of 3.4% (95% CI: -44.8 to 35.5) against primary care consultation with laboratory-confirmed influenza and -2.3% (95% CI: -56.2 to 33.0) for A(H3N2). The low VE reflects mismatch between circulating viruses and the 2014/15 northern hemisphere A(H3N2) vaccine strain. Early use of antivirals for prophylaxis and treatment of vulnerable populations remains important.

• 出版日期2015-2-5