Use of sugammadex in a patient with progressive muscular atrophy and in a patient with amyotrophic lateral sclerosis: Case report

作者：Yoo Jae Hwa^*; Kim Soon Im; Park Sun Young; Jun Mi Roung; Kim Yong Eun; Kim Hyoung June

来源：Medicine, 2017, 96(23): e7098.

DOI：10.1097/MD.0000000000007098

• amyotrophic lateral sclerosis
• progressive muscular atrophy
• sugammadex

Introduction:We herein present 2 cases involving the combination of rocuronium and sugammadex in patients with motor neuron disease. The patients were a 54-year-old man with progressive muscular atrophy who underwent removal of internal fixators in the arm and leg, and a 66-year-old woman with amyotrophic lateral sclerosis who underwent skin grafting in the left lower leg. General anesthesia was induced with propofol, rocuronium, and remifentanil and maintained with desflurane and remifentanil. At the end of the surgical procedure, we administered sugammadex. Three or 4 minutes after administration of sugammadex, the patients began to breathe spontaneously and were extubated without complications.Conclusion:Sugammadex can be used successfully to reverse neuromuscular blockade in patients with motor neuron disease.

• 出版日期2017-6