A case of Mycobacterium mucogenicum infection in a liver transplant recipient and a review of the literature

作者：Maybrook R J^*; Campsen J; Wachs M E; Levi M E

来源：Transplant Infectious Disease, 2013, 15(6): E260-E263.

DOI：10.1111/tid.12154

• liver transplant
• Mycobacterium mucogenicum
• Mycobacterium chelonae
• nontuberculous mycobacteria
• NTM
• peritonitis

Bacterial, viral, and fungal infections can be devastating in a postoperative liver transplant recipient on multidrug immunosuppressive therapy. Various atypical (nontuberculous mycobacteria [NTM]) mycobacterial infections have been reported in the solid organ transplant population, but to our knowledge, no cases of Mycobacterium mucogenicum infections have been reported. Here, we report a case of a patient with end-stage liver disease secondary to primary biliary cirrhosis, model for end-stage liver disease score of 29, who underwent deceased-donor orthotopic liver transplantation, with her postoperative course complicated by multiple pleural effusions and peritonitis. Despite numerous courses of antibiotics, her condition did not improve. Acid-fast bacilli cultures grew M.mucogenicum, which was then treated with appropriate antimicrobical therapy. M.mucogenicum, a rapidly growing NTM that can be present in water contamination, should be recognized as a potential source of infection, especially in the immunocompromised population.

• 出版日期2013-12