A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs

作者：Jang Sung Wan; Suh Won Se; Kim Chung Sub; Kim Ki Hyun; Lee Kang Ro^*

来源：Archives of Pharmacal Research, 2015, 38(11): 1943-1951.

DOI：10.1007/s12272-015-0610-y

• Spiraea prunifolia var. simpliciflora
• Phenolic glycoside
• Cytotoxicity

The phytochemical investigation of the methanol extract from the twigs of Spiraea prunifolia var. simpliciflora (Rosaceae) using column chromatography led to the isolation of a new phenol glycoside, 1-O-(E)-caffeoyl-2-O-p-(E)-coumaroyl-beta-d-glucopyranose (1), together with 16 known phenolic compounds (2-17). The structure of this new compound was elucidated by analysis of spectroscopic data including 1D, 2D nuclear magnetic resonance and HR-FAB-MS data. The isolated compounds were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.

• 出版日期2015-11