Advances in the Synthesis of alpha-Aryl Vinylphosphonates

作者:Shi Bochao; Fang Yewen*; Zhang Li; Jin Xiaoping*; Wu Yonghui; Fang Mei; Yang Yufei; Chen Chong
来源:Chinese Journal of Organic Chemistry, 2016, 36(4): 673-686.
DOI:10.6023/cjoc201601023

摘要

alpha-Aryl vinylphosphonates are an important class of organophosphorus compounds and synthetic intermediates for other organophosphorus molecules. The progress of transition-metal-catalyzed synthesis of alpha-aryl vinylphosphonates including hydrophosphorylation reactions, C-C cross-coupling reactions and C-P cross-coupling reactions is reviewed. The synthetic methods under metal-free conditions are also summarized The organic transformations of alpha-aryl vinylphosphonates and their applications in the synthesis of fosmidomycin analogues are also highlighted.

  • 出版日期2016-4
  • 单位宁波工程学院; 太原理工大学; 浙江医药高等专科学校

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