Angular domain transillumination imaging optimization with an ultrafast gated camera

作者：Vasefi Fartash; Najiminaini Mohamadreza; Ng Eldon; Kaminska Bozena; Chapman Glenn H; Carson Jeffery J L^*

来源：Journal of Biomedical Optics, 2010, 15(6): 061710.

DOI：10.1117/1.3505020

• optical imaging
• angular filter array
• scattering
• spatial filtering
• time domain imaging
• quasi-ballistic photons

By employing high-aspect-ratio parallel microchannels as an angular filter, quasiballistic photons sensitive to internal structures in a turbid medium can be captured. Scattered photons exiting the turbid medium typically exhibit trajectories with random angles compared to the initial trajectory and are mostly rejected by the filter. However, angular filter arrays cannot differentiate between quasiballistic photons (early arriving) and photons that happen to attain a scattered trajectory that is within the acceptance angle (late arriving). Therefore, we have two objectives: (1) to experimentally characterize the angular distribution and proportion of minimally deviated quasiballistic photons and multiply scattered photons in a turbid medium and (2) to combine time and angular gating principles so that early and late arriving photons can be distinguished. From the angular distribution data, the angular filter with angular acceptance about 0.4 deg yields the highest image contrast for transillumination images. The use of angular domain imaging(ADI) with time-gating enables visualization of submillimeter absorbing objects with approximately seven times higher image contrast compared to ADI in a turbid medium with a scattering level of six times the reduced mean free path.

• 出版日期2010-12