Discrimination of the Cognitive Profiles of MCI and Depression using the KBNA

作者:Monette Michelle C E; Leach Larry*
来源:Canadian Journal of Neurological Sciences, 2013, 40(5): 670-677.
DOI:10.1017/S0317167100014906

摘要

Objective: The current study sought to determine if the Kaplan-Baycrest Neurocognitive Assessment (KBNA) was capable of discriminating individuals with subjective memory complaints associated with depression from individuals with mild cognitive impairment (MCI). Methods: Scores on 12 subtests of the KBNA were compared for 27 participants with MCI and 28 participants being treated for depression using Bonferroni correct between-group comparisons for each subtest. KBNA subtest scores were corrected for age and education. Results: Significant between-group differences were obtained on six subtests with large effect sizes (Cohen%26apos;s d) ranging from 1.19 - 1.58. The six subtests involved encoding and delayed episodic memory for verbal and visual information. Using logistic regression analysis, five subtests of the KBNA were able to correctly classify 96.4% of study participants. Conclusion: The results from this preliminary investigation indicate that the KBNA has the potential to serve as a brief and reliable assessment tool capable of distinguishing individuals with subjective memory complaints associated with depression from individuals with MCI in a clinical setting. Limitations of the current study and future research are discussed.

  • 出版日期2013-9