ANALYSIS ON 113 CASES OF ADVERSE REACTIONS CAUSED BY B-LACTAM ANTIBIOTICS

作者:Lu, Jianquan*; Cai, Chunyue; Gu, Yufeng; Tang, Yanhui; Xue, Jinbiao; Huang, Kaijian
来源:African Journal of Traditional, Complementary and Alternative Medicines, 2013, 10(4): 83-87.
DOI:10.4314/ajtcam.v10i4.14

摘要

The objectives of this study were to learn about the characteristics and rules of the occurrence of adverse reactions caused by lactam antibiotics and provide a reference for clinical drug use. Methods: A retrospective study was made to analyse the 113 case reports of adverse reactions caused by beta-lactam antibiotics collected in our hospital between 2007 and 2009. Results: 113 cases of ADR involved 17 kinds of beta-lactam antibiotics, headed by ceftriaxone sodium. The most common manifestation was skin and accessory damage; nervous system and gastrointestinal system damage were also easier to find, and the administration route was mainly intravenous infusion. Conclusion: The clinical application of beta-lactam antibiotics should pay attention to adverse reaction monitoring and rational drug use to reduce the incidence of adverse reactions.

全文