科研之友
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摘要
A series of novel 5'-labelled uridine with fluorophores: N-alkylcarbazole, alkyloxynaphthalene and alkylfluorene were synthesized through H-phosphonate by Arbuzov reaction, and were characterized by using H-1 NMR, P-31 NMR and ESI-MS analysis. The fluorescence spectra of all the compounds in solution and solid powder were described. The experimental results showed that the fluorescence emission intensity of 5'-labelled uridine is very sensitive to solvents.
