A molecule-imprinted polyaniline membrane modified on carbon fiber for detection of glycine

作者：Zeng, Hongjuan^*; Wang, Deshun; Yu, Junsheng

来源：Bio-medical Materials and Engineering, 2014, 24(1): 1085-1091.

DOI：10.3233/BME-130907

• Glycine
• polyaniline
• imprint
• film
• cerebrospinal fluid

A layer of L-glycine-molecule-imprinted polyaniline (LMIP-PANI) polymer film has been modified on a carbon fiber electrode for the determination of L-glycine standard samples and L-glycine in cerebrospinal fluid of wistar mice. It has been found that a linear relationship exists between current and concentration for the glycine standard samples in the range of 0-12 mu M by using the LMIP-PANI-modified carbon fiber electrode as a sensor. However, there is no any relationship between current and concentration for the carbon fiber electrode modified with no-glycine-molecule-imprinted polyaniline (NIP-PANI). The MIP-PANI- and NIP-PANI-modified carbon fiber films have been characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and electrochemistry methods. The investigation shows that the MIP-PANI-imprinted carbon fiber electrode will have a potential application in in-situ monitoring neurotransmitter due to its easy fabrication, low cost, bio-compatibility and flexibility.

• 出版日期2014
• 单位电子科技大学