An aspect of selecting resolving agents: The role of differences in molecule length in diastereomeric salt resolutions

作者：Szeleczky Zsolt; Semsey Sandor; Bagi Peter; Fodi Balazs; Faigl Ferenc; Palovics Emese; Fogassy Elemer^*

来源：Separation Science and Technology (Philadelphia), 2016, 51(4): 727-732.

DOI：10.1080/01496395.2015.1117105

• molecule length
• Diastereomeric salt resolution
• resolving agent
• optical resolution

In the course of 49 individual experiments of diastereomeric salt resolution we have examined the effect of the difference between the racemic and resolving agent molecule lengths on the resolution. We concluded that using resolving agents with the molecule length differing by 3 to 6 from the racemic molecule produces the best result.

• 出版日期2016-3-3