An effective amperometric biosensor based on graphene modified gold nanowire arrays for glucose detection

作者：Hui, Jianing; Cui, Jiewu; Liu, Lingjuan; Xu, Guangqing; Wu, Yucheng^*

来源：Chinese Science Bulletin, 2014, 59(17): 2012-2016.

DOI：10.1007/s11434-014-0230-9

• Gold nanowires
• Graphene
• Electrochemistry
• Glucose biosensor

A novel glucose biosensor based on graphene nanosheets (GNs) modified gold nanowire arrays (AuNWAs) electrode was constructed. Highly ordered gold nanowire arrays were prepared by direct electrodeposition in anodic aluminum oxide templates. GNs were synthesized through a public route involving graphite oxidation, exfoliation, and chemical reduction. Field emission scanning electron microscope and high-resolution transmission electron microscope were employed to characterize the as-prepared AuNWAs and GNs. Glucose oxidase was immobilized on the surface of GNs-AuNWAs modified electrode via a cross-linking method. The cyclic voltammetry results showed that the GNs-AuNWAs-based glucose biosensors have high catalysis activity to hydrogen peroxide (H2O2) than those modified with GNs or AuNWAs only. Furthermore, amperometric response was employed to detect glucose concentration owing to its simplicity, high selectivity, and relative low cost. Glucose biosensors based on GNs-AuNWAs showed excellent performance with high sensitivity of 40.25 mu A cm(-2) (mmol/L)(-1), low detection limit of 0.02 mmol/L, and a linear range from 0.02 to 3 mmol/L.

• 出版日期2014-6
• 单位合肥工业大学