A case of IgG4-related pulmonary disease with rapid improvement

作者：Umeda Masataka; Fujikawa Keita; Origuchi Tomoki^*; Tsukada Toshiaki; Kondo Akira; Tomari Shinya; Inoue Yuichi; Soda Hisashi; Nakamura Hideki; Matsui Shoko; Kawakami Atsushi

来源：Modern Rheumatology, 2012, 22(6): 919-923.

DOI：10.1007/s10165-012-0600-6

• IgG4-related disease
• Interstitial pneumonia
• Respiratory involvement

We report a 72-year-old man with respiratory involvement of immunoglobulin G4 (IgG4)-related disease, who developed dry cough and shortness of breath on effort. The chest computed tomography scan image showed massive and diffuse ground-glass opacity, interlobular thickening, and bronchial wall thickening. The infiltration of IgG4-positive plasma cells in the transbronchial lung biopsy and high serum IgG4 concentrations were found. The patient was treated with 0.6 mg/kg oral prednisolone and showed rapid improvement. This is a case of IgG4-related disease in which the only complication was respiratory involvement.

• 出版日期2012-11