Analysis of heart rate and oxygen uptake kinetics studied by two different pseudo-random binary sequence work rate amplitudes

作者：Drescher U^*; Koschate J; Schiffer T; Schneider S; Hoffmann U

来源：Respiratory Physiology & Neurobiology, 2017, 240: 70-80.

DOI：10.1016/j.resp.2017.03.001

• Kinetics analysis
• Oxygen uptake
• Venous return
• Physiological modeling
• Moderate exercise intensity

Purpose: The aim of the study was to compare the kinetics responses of heart rate (HR), pulmonary (VO(2)pulm) and predicted muscular (VO(2)musc) oxygen uptake between two different pseudo-random binary sequence (PRBS) work rate (WR) amplitudes both below anaerobic threshold.
Methods: Eight healthy individuals performed two PRBS WR protocols implying changes between 30 W and 80 W and between 30 W and 110 W. HR and VO(2)pulm were measured beat-to-beat and breath-by breath, respectively. VO(2)musc was estimated applying the approach of Hoffmann et al. (Eur J Appl Physiol 113: 1745-1754, 2013) considering a circulatory model for venous return and cross-correlation functions (CCF) for the kinetics analysis.
Results: HR and VO(2)musc kinetics seem to be independent of WR intensity (p > 0.05). VO(2)pulm kinetics show prominent differences in the lag of the CCF maximum (39 +/- 9 s; 31 +/- 4 s; p < 0.05).
Conclusions: A mean difference of 14 W between the PRBS WR amplitudes impacts venous return significantly, while HR and VO(2)musc kinetics remain unchanged.

• 出版日期2017-6