A Circuit Model of Real Time Human Body Hydration

作者：Asogwa Clement Ogugua^*; Teshome Assefa K; Collins Stephen F; Lai Daniel T H

来源：IEEE Transactions on Biomedical Engineering, 2016, 63(6): 1239-1247.

DOI：10.1109/TBME.2015.2491964

• Attenuation
• body mass index (BMI)
• galvanic coupling
• hydration
• metabolic rate
• signal propagation

Changes in human body hydration leading to excess fluid losses or overload affects the body fluid's ability to provide the necessary support for healthy living. We propose a time-dependent circuit model of real-time human body hydration, which models the human body tissue as a signal transmission medium. The circuit model predicts the attenuation of a propagating electrical signal. Hydration rates are modeled by a time constant tau, which characterizes the individual specific metabolic function of the body part measured. We define a surrogate human body anthropometric parameter theta by the muscle-fat ratio and comparing it with the body mass index (BMI), we find theoretically, the rate of hydration varying from 1.73 dB/min, for high theta and low tau to 0.05 dB/min for low theta and high tau. We compare these theoretical values with empirical measurements and show that real-time changes in human body hydration can be observed by measuring signal attenuation. We took empirical measurements using a vector network analyzer and obtained different hydration rates for various BMI, ranging from 0.6 dB/min for 22.7 kg/m(2) down to 0.04 dB/min for 41.2 kg/m(2). We conclude that the galvanic coupling circuit model can predict changes in the volume of the body fluid, which are essential in diagnosing and monitoring treatment of body fluid disorder. Individuals with high BMI would have higher time-dependent biological characteristic, lower metabolic rate, and lower rate of hydration.