Diiodoindium(III) Cation, InI2+, a Potent Yneophile. Generation and Application to Cationic Cyclization by Selective pi-Activation of C C

作者：Surendra Karavadhi; Corey E J^*

来源：Journal of the American Chemical Society, 2014, 136(31): 10918-10920.

DOI：10.1021/ja506502p

The removal of the iodide ion from indium triiodide by means of reactive Ag(I) salts leads to the formation of the highly reactive ligandless cation InI2+, which is unusual in having two vacant low-lying p-orbitals. This bivalent Lewis acidity leads to an especially high affinity for the two orthogonal pi-bonds of carbon-carbon triple bonds. Consequently, the double-coordinating InI2+ is an especially effective reagent for the selective activation of C C and the catalytic initiation of cationic cyclization processes. A number of such reactions are described to demonstrate synthetic utility.

• 出版日期2014-8-6