Acute Post-streptococcal Glomerulonephritis with Acute Kidney Injury in Nephrotic Syndrome with the Glomerular Deposition of Nephritis-associated Plasmin Receptor Antigen

作者：Kokuzawa Ayako; Morishita Yoshiyuki^*; Yoshizawa Hiromichi; Iwazu Kana; Komada Takanori; Akimoto Tetsu; Saito Osamu; Oda Takashi; Takemoto Fumi; Ando Yasuhiro; Muto Shigeaki; Yumura Wako; Kusano Eiji

来源：Internal Medicine, 2013, 52(18): 2087-2091.

DOI：10.2169/internalmedicine.52.0103

• acute post-streptococcal glomerulonephritis
• acute kidney injury
• nephrotic syndrome
• nephritis-associated plasmin receptor (NAPlr)

We herein report the case of a 17-year-old man who developed an increased plasma creatinine level (11.1 mg/dL) and oliguria with massive proteinuria (27.3 g/day) four weeks after an abraded wound to his right knee. The histology of the renal biopsy specimens showed diffuse endocapillary proliferative glomerulonephritis with the deposition of nephritis-associated plasmin receptor in the glomerulus. A case of acute kidney injury due to nephrotic syndrome caused by acute post-streptococcal glomerulonephritis was diagnosed. His renal function and proteinuria were improved with supportive care, including hemodialysis, without the administration of immunosuppressive

• 出版日期2013