Association of Quadriceps Muscle Fat With Isometric Strength Measurements in Healthy Males Using Chemical Shift Encoding-Based Water-Fat Magnetic Resonance Imaging

作者：Baum Thomas; Inhuber Stephanie; Dieckmeyer Michael; Cordes Christian; Ruschke Stefan; Klupp Elisabeth; Jungmann Pia M; Farlock Rosanna; Eggers Holger; Kooijman Hendrik; Rummeny Ernst J; Schwirtz Ansgar; Kirschke Jan S; Karampinos Dimitrios C

来源：Journal of Computer Assisted Tomography, 2016, 40(3): 447-451.

DOI：10.1097/RCT.0000000000000374

• muscle fat
• muscle strength
• magnetic resonance imaging
• proton density fat fraction

Magnetic resonance-based assessment of quadriceps muscle fat has been proposed as surrogate marker in sarcopenia, osteoarthritis, and neuromuscular disorders. We presently investigated the association of quadriceps muscle fat with isometric strength measurements in healthy males using chemical shift encoding-based water-fat magnetic resonance imaging. Intermuscular adipose tissue fraction and intramuscular proton density fat fraction correlated significantly (P < 0.05) with isometric strength (up to r = -0.83 and -0.87, respectively). Reproducibility of intermuscular adipose tissue fraction and intramuscular proton density fat fraction was 1.5% and 5.7%, respectively.

• 出版日期2016-6