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摘要
2-Amino-4H-pyrans and tetrahydro-4H-chromenes were readily prepared via a one-pot, three-component reaction of an aldehyde, malononitrile, and ethyl acetoacetate or 5,5-dimethyl-1,3-cyclohexanedione in the presence of anhydrous piperazine as an efficient and recyclable organocatalyst under solvent-free ball-milling at ambient temperature, with high to quantitative yields.
- 出版日期2013-8
