Next-generation optical technologies for illuminating genetically targeted brain circuits

作者:Deisseroth Karl*; Feng Guoping; Majewska Ania K; Miesenbock Gero; Ting Alice; Schnitzer Mark J
来源:Journal of Neuroscience, 2006, 26(41): 10380-10386.
DOI:10.1523/JNEUROSCI.3863-06.2006

摘要

Emerging technologies from optics, genetics, and bioengineering are being combined for studies of intact neural circuits. The rapid progression of such interdisciplinary "optogenetic" approaches has expanded capabilities for optical imaging and genetic targeting of specific cell types. Here we explore key recent advances that unite optical and genetic approaches, focusing on promising techniques that either allow novel studies of neural dynamics and behavior or provide fresh perspectives on classic model systems.

  • 出版日期2006-10-11