科研之友
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摘要
A novel macrocyclic lactone (1) was isolated from the fermentation broth of Streptomyces microflavus neau3, and the structure was elucidated by extensive spectroscopic analysis. Compound 1 showed high acaricidal activity against adult mites (IC(50) = 11.1 mu g mL (1)), and nematocidal activity against Caenorhabditis elegans (IC(50) = 17.4 mu g mL (1)), especially the acaricidal activity against mite eggs with an IC(50) of 37.1 mu g mL (1), which was relative higher than that of the commercial acaricide and nematocide milbemycins A(3)/A(4).
- 出版日期2011-9-15
- 单位东北农业大学
