Assessment of Antibody Responses in Local and Immigrant Residents of Areas with Autochthonous Malaria Transmission in Greece

作者：Piperaki Evangelia Theofano; Mavrouli Maria; Tseroni Maria; Routsias John; Kallimani Athina; Veneti Lamprini; Georgitsou Maria; Chania Maria; Georgakopoulou Theano; Hadjichristodoulou Christos; Tsakris Athanassios^*

来源：The American Journal of Tropical Medicine and Hygiene, 2015, 93(1): 153-158.

DOI：10.4269/ajtmh.14-0420

Greece has been officially malaria free since 1974. However, from 2009 to 2012, several locally acquired, cases of Plasmodium vivax malaria were detected, in immigrants and in Greek citizens. In this study, the antibody (Ab) response of Greeks and immigrants with documented malaria was initially assessed, followed by an Ab screening of Greeks and immigrant residents of local transmission areas. Of the 38 patients tested,.10.5% of Greeks and 15.7% of immigrants were positive 5-7 months after infection. Of the 1,019 individuals from various areas of Greece, including those of autochthonous transmission, 85 of the 721 (11.8%) immigrants were positive, whereas all 298 Greeks were negative. The rapid Ab titer decline observed is reasonable, given the non-endemic epidemiological setting. The seroepidemiological findings indicate that the local Greek population remains malaria naive and that at this point Greeks are unlikely to serve as reservoir for the infection of local mosquitoes.

• 出版日期2015-7