Metal-Free Direct Oxidation of Aldehydes to Esters Using TCCA

作者:Gaspa Silvia; Porcheddu Andrea; De Luca Lidia*
来源:Organic Letters, 2015, 17(15): 3666-3669.
DOI:10.1021/acs.orglett.5b01579

摘要

Aromatic and aliphatic aldehydes are simply converted into esters by an efficient oxidative esterification carried out under mild conditions. The aldehydes are converted in situ into their corresponding acyl chlorides, which are then reacted with primary and secondary aliphatic, benzylic, allylic, and propargylic alcohols and phenols. A variety of esters are obtained in high yields.

  • 出版日期2015-8-7