Asymmetric construction of all-carbon quaternary stereocenters in the total synthesis of natural products

作者：Chen, Wen; Zhang, Hongbin^*

来源：Science China Chemistry, 2016, 59(9): 1065-1078.

DOI：10.1007/s11426-016-0055-0

• all-carbon quaternary stereocenter
• asymmetric synthesis
• total synthesis
• natural product

Structure units containing all-carbon quaternary stereogenic center are found in many bioactive natural products. However, enantioselective construction of this type of structure units has been a formidable challenge for synthetic community due to the steric hindrance enforced by all-carbon quaternary stereocenters. In this review, we present the achievements made by Chinese scientists in the area of asymmetric synthesis of all-carbon quaternary stereocenters in natural products during the past two years.

• 出版日期2016-9
• 单位云南大学