Asymmetric synthesis of 1-deoxyazasugars from chiral aziridines

作者:Singh Alok; Kim Bongchan; Lee Won Koo*; Ha Hyun Joon
来源:Organic and Biomolecular Chemistry, 2011, 9(5): 1372-1380.
DOI:10.1039/c0ob00730g

摘要

A general and facile synthesis of enantiopure 1-deoxyazasugars was achieved from stereoselective dihydroxylation of a common synthetic intermediate, piperidine ring fused oxazolidin-2-one, originating from a commercially available starting substrate, chiral aziridine-2-carboxylate, in high yields.

  • 出版日期2011