Asymmetric Transfer Hydrogenation of Ketimines by Indoline as Recyclable Hydrogen Donor

作者:Saito Kodai; Miyashita Hiromitsu; Akiyama Takahiko*
来源:Organic Letters, 2014, 16(20): 5312-5315.
DOI:10.1021/ol502486f

摘要

The chiral phosphoric acid catalyzed enantioselective transfer hydrogenation of various ketimines was achieved by the use of 2-aryl indoline as the hydrogen donor. Corresponding chiral amines were obtained in good chemical yields with excellent enantioselectivities.

  • 出版日期2014-10-17