Brain mechanisms of altered consciousness in generalised seizures

作者:Seri Stefano*; Brazzo Daniela; Thai Ngoc J; Cerquiglini Antonella
来源:Behavioural Neurology, 2011, 24(1): 43-46.
DOI:10.3233/BEN-2011-0317

摘要

In spite of the inherent difficulties in achieving a biologically meaningful definition of consciousness, recent neurophysiological studies are starting to provide some insight in fundamental mechanisms associated with impaired consciousness in neurological disorders. Generalised seizures are associated with disruption of the default state network, a functional network of discrete brain areas, which include the fronto-parietal cortices. Subcortical contribution through activation of thalamocortical structures, as well as striate nuclei are also crucial to produce impaired consciousness in generalised seizures.

  • 出版日期2011