A novel organozinc reagent 4-coumarinylzinc bromide; preparation and application in the synthesis of 4-substituted coumarin derivatives

作者：Rieke Reuben D; Kim Seung Hoi^*

来源：Tetrahedron Letters, 2011, 52(24): 3094-3096.

DOI：10.1016/j.tetlet.2011.03.151

A novel organozinc reagent, 4-coumarinylzinc bromide, was prepared by the direct oxidative addition of active zinc to 4-bromocoumarin. The resulting organozinc bromide underwent the palladium-catalyzed cross-coupling reactions with a variety of aryl halides and acid chlorides affording the corresponding coupling products in good yields under mild conditions.

• 出版日期2011-6-15