An "on-off-on" fluorescence assay based on silicon nanoparticles for selective detection of manganese(II)

作者：Meng, Lei; Yuan, Yaqing; Pu, Guang; Xu, Na^*

来源：Analytical Methods, 2017, 9(17): 2553-2560.

DOI：10.1039/c7ay00514h

• ONE-STEP SYNTHESIS
• QUANTUM DOTS
• SENSITIVE DETECTION
• AQUEOUS-SOLUTION
• ION
• NANOCLUSTERS
• BINDING
• CELLS
• PROBE
• NEUROTOXICITY

Highly blue luminescent and water-soluble silicon nanoparticles (Si NPs) are prepared by an efficient one-pot hydrothermal route from (3-aminopropyl) trimethoxysilane and ascorbic acid at 160 degrees C. The label-free Si NPs are demonstrated as an effective fluorescent probe for selective recognition of Mn2+. The linear range is from 2.5 to 250 mu M and the detection limit is calculated to be 1.1 mu M due to Mn2+ induced Si NP aggregation (turn-off). Additionally, the quenched fluorescence can be restored in the presence of EDTA because the EDTA can grab Mn2+ from the aggregated Si NPs-Mn2+ system owing to its strong chelating ability (turn-on). This sensing system based on the "on-off-on" fluorescence switching method can facilitate further development in Mn2+ detection.

• 出版日期2017-5-7
• 单位吉林化工学院