科研之友
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摘要
Objectives: A new generation of neuromuscular electrical stimulation (NMES) devices can exercise aerobically at equivalent rates to voluntary exercise. Many with type 2 diabetes cannot or will not exercise sufficiently. The objective of this pilot investigation was to see (1) if it was an acceptable training modality for men with type 2 diabetes mellitus and (2) to assess effects on haemoglobin A1c levels. %26lt;br%26gt;Design, setting, participants and intervention: A case series of eight men with type 2 diabetes mellitus (aged 53+/-8; body mass index 32+/-5 5 kg/m(2)) trained with the NMES system for 1 h 6 times weekly for 8 weeks, unsupervised, at home. There were no other medication or lifestyle interventions. The aerobic NMES exercise system delivers a repeating set of four complex staggered pulses at high intensities (typically 100 mA+) through an array of eight thigh electrodes. %26lt;br%26gt;Outcome measures: The primary outcome measures were changes in haemoglobin A1c and the responses in a questionnaire on participants%26apos; perceptions of the system. Body mass and composition were also measured before and after the NMES intervention period. %26lt;br%26gt;Results: All participants could use the system at a level that left them breathless and sweaty and with a heart rate over 120 beats per minute. Haemoglobin A1c levels improved by 0.8+/-0.7% from 7.4+/-1.3% (mean +/- SD) to 6.6+/-1.0% (p=0.01). All participants considered the system suitable for people with diabetes, would recommend it and would continue to use it twice a week %26apos;to maintain improvements%26apos;. %26lt;br%26gt;Conclusions: These results suggest that aerobic NMES may be acceptable and have a beneficial effect on haemoglobin A1c of some men with diabetes. The treatment may be of particular benefit in those who will not or cannot do adequate amounts of voluntary exercise. A randomised control trial is required for conclusive efficacy data.
- 出版日期2012
