A new quinoline-based chemosensor for Zn2+ ions and their application in living cell imaging

作者:Ponnuvel Kandasamy; Kumar Madasamy; Padmini Vediappen*
来源:Sensors and Actuators B: Chemical , 2016, 227: 242-247.
DOI:10.1016/j.snb.2015.12.017

摘要

The synthesis and evaluation of new quinoline based fluorescent chemosensor L1 for the detection of Zn2+ in THE/H2O. The absorption and fluorescent spectra change was observed upon addition of Zn2+ indicate that L1 is highly selective for Zn2+ over other metal ions. The probe displayed an apparent color change while addition of Zn2+, which could be observed by the naked eye under a UV lamp. The experimental results have been verified with DFT and TDDFT calculation. In vitro sensitivity to Zn2+ was demonstrated in Hela cells with the use of fluorescence confocal microscopy.

  • 出版日期2016-5