Daily 10 mg rivaroxaban as a therapy for ventricular thrombus related to left ventricular non-compaction cardiomyopathy A case report

作者：Sun, Huan; Zhao, Qini; Wang, Yanjing; Lakin, Robert; Feng, Haiyan; Fan, Xingyu; Luo, Huiling; Gao, Dongmei; Liu, Lin; He, Yuquan^*; Yang, Ping

来源：Medicine, 2018, 97(4): e9670.

DOI：10.1097/MD.0000000000009670

• anticoagulation
• LVNC
• NOACs

Rationale: Left ventricular non-compaction cardiomyopathy (LVNC) is a rare heart disorder related to thrombosis. Anticoagulant therapy is suggested for the treatment of this disease. The success of the novel oral anticoagulant rivaroxaban as a treatment option for this disorder is unclear. @@@ Patient concerns: A 43-year-old man who felt dizzy at rest was found to have an intraventricular thrombus. @@@ Diagnoses: The thrombus was confirmed by echocardiography. And LVNC was diagnosed by cardiac magnetic resonance (CMR) and echocardiography. @@@ Interventions: He was prescribed a low dose (10mg daily) of rivaroxaban as treatment. @@@ Outcomes: After 3 months, the thrombus diminished, and the manifestation disappeared. @@@ Lessons: Low dose of rivaroxaban may serve as a viable option for anticoagulation therapy in LVNC patients, with large clinical trials needed to determine the best course of treatment.

• 出版日期2018-1
• 单位吉林大学