An efficient biomimetic cleavage of gem-diacetates to aldehydes by beta-cyclodextrin under neutral conditions in aqueous medium

作者：Reddy MA; Reddy LR; Bhanumathi N; Rao KR^*

来源：Synthetic Communications, 2002, 32(2): 273-277.

The cleavage of gem-diacetates to aldehydes, a widely used protecting group in organic synthesis, has been achieved for the first time under neutral conditions in aqueous medium using P-cyclodextrin as catalyst. The main advantage of the present methodology is that it can be used with compounds having a variety of functional groups since the cleavage is carriedout under neutral conditions in aqueous medium.

• 出版日期2002